Fig 1.
Flowchart for patient inclusion.
ANA, antinuclear antibody; AILD, autoimmune liver diseases.
Table 1.
Demographic and clinical characteristics of the enrolled patients with positive cytoplasmic ANA patterns.
Fig 2.
Representative images of the cytoplasmic antinuclear-antibody staining pattern in HEp-2 cells by using the sera of AILD or non-AILD patients.
The reticular pattern shows granular and filamentous staining throughout the cytoplasm, whereas the speckled pattern shows fine speckles distributed throughout the cytoplasm. The reticular (A) and speckled (B) patterns in patients with primary biliary cholangitis, the reticular pattern in a patient with hepatitis B (C), and the speckled pattern in an osteoarthritis patient (D).
Table 2.
Cytoplasmic ANA patterns of patients with and without AILD.
Table 3.
Clinical characteristics of patients with AILD based on the cytoplasmic ANA patterns.
Table 4.
Nuclear patterns and titers of ANA in patients with AILD based on the cytoplasmic ANA patterns.
Table 5.
Subgroup analysis of patients with reticular cytoplasmic ANA pattern based on AMA serology.