Table 1.
Overview of demographic, disease and DBS-related data.
Fig 1.
Localization of DBS electrodes within the STN.
A: DBS electrodes localizations from thirteen participants in relation to the STN. Electrodes have been reconstructed in MNI space. Red contacts represent clinically active contacts. B: Spatial distribution of active contacts in relation to different STN segments (from DISTAL atlas). All 26 active contacts (red spheres) are projected cumulatively onto the left hemisphere (right contacts have been flipped). Subcortical structures including STN segments were defined from DISTAL subcortical atlas implemented in Lead-DBS [68]. Backdrop is from the high resolution 100 micron postmortem MRI in Edlow et al. [72]. Please note that due to missing post-operative MRI the data from participant no. 8 did not enter the localization analysis. GPe: globus pallidus externus, GPi: globus pallidus internus, RN: red nucleus, STN: subthalamic nucleus.
Table 2.
Linguistic parameters in the STN DBS ON and OFF condition.
Fig 2.
Correlations between VAT overlap with associative vs. motor STN and language vs. motor changes.
A: VAT overlap (light orange area) with the associative area (green area) of the STN is depicted on the left; scatter diagrams on the right indicate correlations between VAT overlap with the associative STN and the increase in clause (right, bottom) and word (right, center) production. B: VAT overlap (light orange area) with the motor area (blue area) of the STN depicted on the left and the scatter diagram on the right indicate a correlation between VAT overlap with the motor STN and UPDRS improvement.