Fig 1.
Angiography-based assessment of wall shear in obstructive coronary lesions.
CFD analysis was performed in models reconstructed from two angiographic projections (A); Mean WSS was calculated in the whole lesion and three lesion sub-segments: proximal, middle and distal. OCT imaging was performed in the same lesion to identify TCFA lesions.
Table 1.
Patient baseline characteristics.
Table 2.
Intravascular imaging data.
Table 3.
Angiographically derived measurements and computational fluid dynamics findings.
Fig 2.
High mean wall shear stress in the proximal segment of coronary lesions is associated with the presence thin-cap fibroatheroma verified by optical coherence tomography.
Color-coded WSS maps for two representative cases from patients with (A) thin-cap fibroatheroma lesion identified by OCT with minimal fibrous cap thickness 60 μm (A, inset) and WSS measured in the proximal segment of the lesion 16.5 Pa and (B) lesion with thick fibrous cap of 170 μm (B, inset) and proximal WSS 3.81 Pa. FCT = fibrous cap thickness; TCFA = thin-cap fibroatheroma; WSS = wall shear stress.
Table 4.
Relationship between TCFA and hemodynamics.