Table 1.
Adherence of the 356 included patients to post-operative follow up (example for 8-oxoGuo).
Fig 1.
Subdivision according to diabetes status.
Marked with grey color are the groups discussed in this paper. NDH, patients without diabetes; NDH, patients with type 2 diabetes; DH-NDH, patients with diabetes who obtained remission in diabetes after RYGB; DH-DH, patients with diabetes who did not obtain remission in diabetes after RYGB. Twenty-three patients did not fit in any of the groups NDH, DH-NDH or DH-DH.
Table 2.
Preoperative characteristics for the three main study population subgroups.
Table 3.
Preoperative excretion of 8-oxodG and 8-oxoGuo for female and male patients with and without diabetes.
Fig 2.
Changes in oxidative stress to DNA and RNA after Roux-en-Y gastric bypass surgery.
The figures show 24-hour pre- and postoperative excretion of 8-oxodG (Fig A) and 8-oxoGuo (Fig B) in the whole study population. Data are reported as means with error bars showing the 95% confidence interval of the mean and * symbolizes a significant difference after Bonferroni correction. The number of patients, n, at each time point is shown at the bottom of each figure.
Fig 3.
Differences in oxidative stress to DNA and RNA depending on diabetes status.
The Figs A & B report data for the female subpopulation divided in two subgroups: patients without diabetes (white bars) and patients with diabetes (black bars). Fig C reports data for the female subpopulation divided in three subgroups: NDH, patients without diabetes (white bars); DH-NDH, patients with diabetes who obtained remission in diabetes after RYGB (dotted bars) and DH-DH, patients with diabetes who did not obtain remission in diabetes after RYGB (black bars). Data are reported as means with error bars showing the 95% confidence interval of the mean and * symbolizes a significant difference after Bonferroni correction. The number of patients, n, at each time point is shown at the bottom of each figure.
Fig 4.
Relative changes in body weight, BMI and markers of glucose metabolism after RYGB.
Data are means of levels relative to the preoperative means (in percent) for body weight and BMI (diamonds), C-peptide (black circles), fasting glucose (x’es), HbA1c (triangles), HOMA2-IR (white circles) and Insulin (squares).
Table 4.
Correlations between 8-oxodG, 8-oxoGuo, BMI and markers of glucose and lipid metabolism.