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Fig 1.

Flow chart of literature retrieval.

In total, 507, 53, 0, 242, and 295 articles were found in Embase, PubMed, Cochrane Library, CNKI, and Wanfang Data, respectively.

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Table 1.

Characteristics of the included studies.

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Table 1 Expand

Fig 2.

Methodological quality graphs (risk of bias and applicability concerns) were presented as percentages across the included studies using a composite reference standard.

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Fig 3.

Forest plot for the sensitivity and specificity of mNGS for the diagnosis of tuberculosis meningitis using a composite reference standard.

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Table 2.

Meta-regression analysis for different parameters.

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Table 2 Expand