Fig 1.
Representation of the structural SD-OCT layers segmentation for superficial capillary plexus (SCP) and deep capillary plexus (DCP).
Fig 2.
Panel A: Representation of the OCTA assessment of the superficial capillary plexus (SCP). The SCP was investigated in two different OCTA scan modalities: (i) 3x3-mm single volume scan (V1) (Top left), and (ii) 3x3 multiple-volume scan (V4) (bottom left). The SCP binarized (middle) and skeletonized (right) images, for both protocol scans, were analyzed to investigate both perfusion density (PD), and vessel length density (VLD), respectively. Panel B: Representation of the OCTA assessment of the deep capillary plexus (DCP). The DCP was investigated in two different OCTA scan modalities: (i) 3x3-mm single volume scan (V1) (top left), and (ii) 3x3 multiple-volume scan (V4) (bottom left). The DCP binarized (middle) and skeletonized (right) images, for both protocol scans, were analyzed to investigate both perfusion density (PD), and vessel length density (VLD), respectively.
Fig 3.
Representation of the OCTA assessment of the choriocapillaris (CC).
The CC was investigated in two different scans: (i) 3x3-mm single volume scan (V1) (top left), and (ii) 3x3 multiple-volume scan (V4) (bottom left). The CC binarized (right) image was analyzed to investigate CC flow deficits.
Fig 4.
Bland-Altman plots to assess concordance between methods reporting mean between methods for SCP PD, SCP VLD, DCP PD, and DCP VLD variables (A) and SCP VDI, DCP VDI, and CC flow deficits variables (B) reporting on x-axis and differences between methods on the y-axis.
Table 1.
Patient characteristis expressed as mean ± SD or n (column %).
Table 2.
Retinal vascular metrics expressed as mean ± SD evaluated for V1 (%), V4 (%) and differences.
Table 3.
Inter-methods repeatability of measurements: CCC = concordance correlation coefficient.