Fig 1.
Mutational landscape of LEB-GBM cohort.
Oncoplot of the 46 remaining candidate genes (rows), after filtering, commonly mutated in GBM. Columns correspond to samples. Colored squares indicate mutated genes and grey squares indicate non-mutated genes. Each color represents a different type of mutation: missense mutation (blue), splice site mutation (light orange), frame shift deletion (light blue), nonsense mutation (light green), multi-hit (dark green), in frame deletion (dark orange), frame shift insertion (pink) and in frame insertion (red). Percentages represent mutation rate among all LEB-GBM patient samples.
Table 1.
Comparison of common GBM gene mutations between the LEB-GBM cohort and the TCGA cohort.