Fig 1.
Comparison between PERG acuity of C57BL/6J and BALB/c mice.
(A) Examples of PERG and noise waveforms from B6 and BALB/c mice at different spatial frequencies and 700 cd/m2 mean luminance. (B) PERG amplitudes as a function of spatial frequency for all mice. Linear regressions of PERG amplitude (blue lines with 95% confidence region) intersect the median noise level (red lines) at different spatial frequencies depending on strain and mean luminance. (C) Mean PERG acuity (± SEM) in B6 and BALB/c in individual mice calculated by linear extrapolation of PERG amplitude to the median noise. (D) Group PERG acuity assessed with the nominal logistic fit showing that acuity depends on strain and luminance. The estimated acuity is the intersection of the logistic curve (blue line) with the 0.50 probability grid line). Data points (blue triangles: SNRs >1, YES; red circles: SNRs ≤1, NO) are jittered along the vertical axis, with no reference to the axis probability scale.
Fig 2.
Comparison between PVEP acuity of C57BL/6J and BALB/c mice.
(A) Examples of PVEP and noise waveforms recorded from B6 and BALB/c mice at different spatial frequencies and 700 cd/m2 mean luminance. (B) PVEP amplitudes as a function of spatial frequency for all mice. Linear regressions of PVEP amplitude (blue lines with 95% confidence region) intersect the median noise level (red lines) at different spatial frequencies depending on strain. (C) Mean PVEP acuity (± SEM) in B6 and BALB/c calculated by linear extrapolation of PVEP amplitude to the median noise in individual mice. (D) Group PVEP acuity assessed with the nominal logistic fit method. The estimated acuity is the intersection of the logistic curve (blue line) with the 0.50 probability grid line). Data points (blue triangles: SNRs >1, YES; red circles: SNRs ≤1, NO) are jittered along the vertical axis, with no reference to the axis probability scale.
Fig 3.
OMR acuity assessed with the nominal logistic fit in C57BL/6J mice.
The estimated acuity is the intersection of the logistic curve (blue line) with the 0.50 probability grid line). Data points (blue triangles: SNRs >1, YES; red circles: SNRs ≤1, NO) are jittered along the vertical axis, with no reference to the axis probability scale. Nominal logistic fit of BALB/c mice is not shown as they were unresponsive to the OMR stimulus.