Fig 1.
The Number Symbol Coding Task.
Fig 2.
Histogram of Number Symbol Coding Task.
This histogram demonstrates that the Number Symbol Coding Task follows a normal distribution with a mean of 30.1, standard deviation of 13.8, and a median of 30.
Table 1.
Construct validity with clinical measures.
Table 2.
Construct validity with neuropsychological measures and patient-reported outcomes.
Table 3.
Performance of Number-Symbol Coding Task by demographics, staging, and diagnoses.
Fig 3.
Discrimination of the Number Symbol Coding Task.
ROC curves comparing the discriminability of the NSCT, patient and caregiver forms of the QDRS to differentiate healthy controls (CDR 0) from individuals with any form of cognitive impairment (CDR>0). The combination of the NSCT, a patient-reported outcome (patient QDRS), and informant-reported outcome (caregiver QDRS) correctly classified 90.8% of cases (see details in text). Key: AUC = Area under the curve; QDRS = Quick Dementia Rating System; NSCT = Number Symbol Coding Task.
Table 4.
Number Symbol Coding Task and volumetric MRI measures.
Table 5.
Clinical profiles of Number Symbol Coding Task scores.