Fig 1.
The content of predominant bacteria in the gut microbiome.
(A) Bacteroidetes, %. (B) Firmicutes, %. (C) Bacteroidetes/ Firmicutes ratio. (D) Actinobacteria, %. * p <0.05, compared to the control on the corresponded day. ## p < 0.01, compared with week 0 in the corresponded experimental group.
Fig 2.
The content of predominant bacteria in the gut microbiome.
(A) Betaproteobacteria, %. (B) Delta- and Gammaproteobacteria, %. (C) Epsilonproteobacteria, %. * p <0.05; ** p < 0.01, compared to the control on the corresponded day. # p < 0.05; ## p < 0.01, compared with week 0 in the corresponded experimental group.
Fig 3.
The content of predominant bacteria in the gut microbiome.
(A) Deferribacteres, %. (B) “Candidatus Saccharibacteria”, %. (C) Verrucomicrobia, %. (D) Tenericutes, %. * p < 0.05; ** p < 0.01, compared to the control on the corresponded day. # p < 0.05; ## p < 0.01; ### p < 0.001, compared with week 0 in the corresponded experimental group.
Table 1.
MB concentration and species composition of bacteria in the gut microbiome.
Fig 4.
Scores in all trials of the T-maze test.
* p < 0.05, compared with the control.
Table 2.
Correlation between gut microbiome composition and results of T-maze test.
Fig 5.
Correlation between the T-maze test scores and content of bacterial groups on the 4th week of treatment.
(A) Correlation between the T-maze test scores in (2nd day) and content of Deferribacteres, %; (B) Correlation between the T-maze test scores (3rd day) and content of Verrucomicrobia, %.