Scheme 1.
Molecular structure of amitriptyline hydrochloride (AMT).
Scheme 2.
Synthesis pathway of the ester bonded gemini surfactant (14-E2-14).
Fig 1.
Surface tension (γ) versus concentration (C) plot for pure 14-E2-14 and AMT+14-E2-14 mixtures in various ratios at 298.15 K: (i) aqueous, (ii) 0.050 mol∙kg-1 NaCl, (iii) 0.50 mol∙kg-1 urea, and (iv) 1.0 mol∙kg-1 urea system.
Fig 2.
Change of cmc/cmcid value of AMT+14-E2-14 mixed system vs. mole fraction (α1) of 14-E2-14 (filled symbol for experimental cmc and open symbol for cmcid).
Table 1.
Various physicochemical parameters for AMT+14-E2-14 mixed system in different solvent at 298.15 K.
Table 2.
Various interfacial parameters for AMT+14-E2-14 mixed system in diverse solvent at 298.15 K.
Table 3.
Different thermodynamic parameters and packing parameter (P) for AMT-14-E2-14 mixed system in diverse solvent at 298.15 K.
Fig 3.
FTIR spectra of (i) AMT in absence and presence of 14-E2-14 and (ii) 14-E2-14 in absence and presence of AMT (both mixtures are in equal ratio).
Fig 4.
UV-visible spectra of AMT in absence and presence of increasing concentrations of 14-E2-14.
Fig 5.
The 10−3 mmol.kg-1 pyrene (PY) solution fluorescence spectra of (i) individual 14-E2-14, and (ii) 14-E2-14 (0.8)+AMT (0.2) micellar mixed system at diverse quencher concentrations in presence of 0.050 mol.kg-1 NaCl.
Table 4.
Aggregation number (Nagg) and different associated parameters for AMT+14-E2-14 mixed system in diverse solvent at 298.15 K.