Fig 1.
CKD: Chronic kidney disease; ESRD: End-stage renal disease; HD: Hemodialysis; ICP: Intracranial pressure.
Table 1.
Clinical characteristics of the study patients*.
Fig 2.
Predialysis and postdialysis noninvasive intracranial pressure (ICP) parameters at the three weekly hemodialysis sessions over the six months of follow-up.
A) Time to peak (TTP). B) P2/P1 ratio. Differences between predialysis and postdialysis intracranial pressure parameters were analyzed by paired Student’s t-test (*p<0.01). Differences in TTP and P2/P1 ratio between the three weekly hemodialysis sessions were analyzed by repeated-measures ANOVA but were not significant (p>0.05). Data are presented as Mean ± SD.
Fig 3.
Comparison of predialysis and postdialysis noninvasive intracranial pressure (ICP) parameters according to the hemodialysis sessions over the six months of follow-up.
(A) Time to peak (TTP). (B) P2/P1 ratio. Box-plots illustrate the median and interquartile range of the noninvasive intracranial pressure parameters at the three weekly hemodialysis sessions (1st, 2nd, and 3rd) over the six months of follow-up (*p<0.05, repeated-measures ANOVA followed by the Tukey’s post-hoc test).
Fig 4.
Mean arterial pressure in the different hemodialysis sessions of the week.
Significant statistical differences were observed for the mean arterial pressure (MAP) parameter when comparing it with the different hemodialysis sessions of the week (1st, 2nd, and 3rd). Different letters, significant differences between the different sessions in the pre- and post-dialysis moments (p<0.05, ANOVA for repeated measures and Tukey’s post-test).
Fig 5.
Interdialytic weight gain in the different hemodialysis sessions of the week.
Significant statistical differences were observed for the interdialytic weight gain parameter when comparing it with the different hemodialysis sessions of the week (1st, 2nd, and 3rd) (p <0.05, ANOVA for repeated measures and Tukey’s post-test).