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Fig 1.

PRISMA flow diagram showing the selection process of retrieved studies.

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Table 1.

Study characteristics of diabetic and non-diabetic pregnant women included in the study.

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Table 2.

Level of specific AGEs and related metabolic biomarkers implicated for diabetic complications.

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Fig 2.

Forest plot depicting the mean level (U/ml) of AGEs in GDM and pregnant controls.

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Fig 3.

Forest plot depicting the BMI of women with GDM and controls.

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Fig 4.

Forest plot comparing the level of HOMA-IR among women with GDM and pregnant controls.

(A) without sensitivity analysis (B) with sensitivity analysis.

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Fig 5.

Forest plot depicting the level of HbA1c among women with GDM and controls.

(A) without sensitivity analysis (B) with sensitivity analysis.

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Fig 6.

Forest plot depicting the level of ICAM-1 and VCAM-1 (ng/ml) among women with GDM and controls.

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Table 3.

Subgroup analysis of outcome measures based on continent, trimester of pregnancy and sample type.

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Fig 7.

Bubble plot depicting the univariate meta regression of SMD with overall sample size.

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Fig 8.

Bubble plot depicting the univariate meta-regression of SMD with years of publication.

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Fig 9.

Meta-influence plot showing the impact of every study on the overall SMD estimate.

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Fig 10.

Funnel plot showing the publication bias of studies.

Small studies with larger effect sizes are shown in the right lower side of the plot.

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