Fig 1.
Concept and construction progress of Prometheus.
Schematic showing the workflow for constructing Prometheus (left), detailed information for each stage (middle), and the functions available within Prometheus (right).
Fig 2.
Construction of primary and secondary databases.
(A) Screenshot of the Genome Archive page. (B) The numbers of species and genome versions used for the construction of Prometheus. (C) Screenshot of the Genome Browser of Prometheus. A region of the human genome (HGP 38) is shown in the inset. (D) Screenshot of the Gene Viewer, which provides detailed information of individual genes. Gene structure, domain architecture, subcellular localization, and orthologous and paralogous genes are shown in each panel.
Table 1.
Statistics of species and their genomic sequences in Prometheus.
Fig 3.
Identification of TFs and genes in the TCA using gene search.
(A) Validation of identified TFs using the iTAK pipeline. (B) Human TCA cycle genes were investigated and used for further analysis. The ratios of each gene are shown as heatmaps.
Fig 4.
Interkingdom comparative analysis of the photolyase/cryptochrome gene family.
(A) Domain architectures of the photolyase/cryptochrome gene family. (B) Taxonomic distribution of photolyase/cryptochrome genes.