Fig 1.
CONSORT flow diagram of the study.
Table 1.
Baseline characteristics of participants based on 10-year Framingham cardiovascular risk scores.
Table 2.
Primary outcome based on stratified cardiovascular risk scores.
Fig 2.
Natural cubic spline curve demonstrating a J-shaped relationship between efficacy of intensive blood pressure reduction and 10-year Framingham cardiovascular risk.
Fig 3.
Cumulative hazards for the primary outcome in intensive and standard treatment groups in participants with a 10-year Framingham cardiovascular risk score >7%.
Table 3.
Primary and secondary outcomes in patients with a 10-year Framingham cardiovascular risk score >7%.
Table 4.
Primary outcome based on subgroups in those with a 10-year Framingham cardiovascular risk score >7%.
Table 5.
Serious adverse events, condition of interest and monitored clinical events in participants with a 10-year Framingham cardiovascular risk score> 7.