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Fig 1.

Tumor budding.

A tumor with low number of buds (marked with black arrows) shown in a, and a tumor with high number of buds in b.

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Table 1.

Shift in T-classification; T-status according to old classification in the first column, the T-status according to TNM8 in the second.

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Table 1 Expand

Table 2.

Spearman bivariate correlation between TB and the variables T, N and DOI in the whole cohort.

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Table 2 Expand

Table 3.

Spearman bivariate correlation between DOI 2-tier, DOI 3-tier and TB/DOI and the variables T and N in the whole cohort.

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Table 3 Expand

Fig 2.

Kaplan Meier survival curves based on TB applying the 2-tier cutoff for TB (A) and the 3-tier cutoff (B).

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Fig 2 Expand

Table 4.

Characteristics of the patients (n = 150) with OTSCC treated in curative intent, including number of cases, percent of patients with disease-specific survival (DSS) with p-value (p), 95% confidence interval (CI), and hazard ratio (HR).

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Table 4 Expand

Table 5.

Low-stage and high-stage disease evaluated separately.

Percentage of 5-year DSS and p-value for each group.

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Table 5 Expand