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Table 1.

Questionnaire.

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Table 2.

Baseline characteristics.

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Table 2 Expand

Table 3.

Side effects.

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Table 3 Expand

Fig 1.

Course of the FEV1 in % predicted for all 12 patients.

Time = 0 means start of the Twincer. One of the patients who started with lumacaftor/ivacaftor and the patient on ivacaftor started 1,5 years before start of the Twincer. One patient on lumacaftor/ivacaftor started around the same time as he started with the Twincer, and the last patient on lumacaftor/ivacaftor started 2 years after start of the Twincer.

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Fig 1 Expand

Table 4.

Mean emitted dose per discharge score at quality control (n = 1036), and frequency per discharge score of all used and returned Twincers (total n = 8544; for discharge score 2–5 than n = 6963).

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Table 4 Expand