Fig 1.
a) The Neighbour-Joining (NJ) tree showing the genetic relationship of the studied populations. The figure was drawn from the Fst distances obtained from the haplotype analysis of Eurasian populations. b) Heat map showing the intra- and inter-population variation measured by average pairwise sequence differences of the ACE2 gene. The average pairwise differences between populations are shown in the upper triangle of the matrix (green). The average number of pairwise differences within each population group are shown along the diagonal (orange). The differences between populations based on Nei's genetic distances are depicted in lower triangle of the matrix (blue). The obtained values of various parameters have been shown at the color scales.
Fig 2.
The median joining (MJ) network of 142 haplotypes belonging to gene ACE2.
Circle sizes are proportional to the number of samples with that haplotype. The three most common haplotypes are marked. The three important SNPs studied in details have been marked in the figure. We used median joining method implemented in the NETWORK programme ver. 5.