Fig 1.
ESD, endoscopic submucosal dissection; RT, radiotherapy; CCRT, concurrent chemoradiotherapy; SESCC, superficial esophageal squamous cell carcinoma; SCC, squamous cell carcinoma
Fig 2.
Endoscopic images of Lugol chromoendoscopy.
(A) No Lugol voiding lesions (LVLs); (B) several (≤10) small LVLs; (C) many (>10) LVLs; (D) many (>10) irregularly shaped multiform LVLs around the main lesion.
Fig 3.
Margin of main Lugol-voiding lesion (LVL).
(A) clear margin of the main LVL; (B) unclear margin of the main LVL; (C) spiculated margin of the main LVL.
Table 1.
Baseline characteristics of patients with versus without metachronous recurrence.
Fig 4.
Metachronous recurrence after endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma occurred in 8.3% of the patients allocated to surveillance (incidence, 28/10000 person-years).
Table 2.
Univariate analysis of the risk factors for metachronous recurrence after endoscopic resection.
Fig 5.
Metachronous recurrence-free survival in patients who underwent endoscopic resection for (A) Lugol-voiding lesion (LVL) and (B) Margin of the main LVL.
Table 3.
Multivariable analysis of risk factors for metachronous recurrence after endoscopic resection.