Table 1.
Parameters for photobiomodulation therapy (PBMT).
Fig 1.
Photomicrographs of histological muscles sections (longitudinal and transversal sections) of WT, placebo-control, PBMT, NSAID and Prednisone groups (HE, original magnification x 400).
Photomicrographs of WT and Placebo-control groups were obtained from a previous study [10].
Fig 2.
Photomicrographs of histological muscles sections (longitudinal and transversal sections) of WT, placebo-control, PBMT + Prednisone and PBMT + NSAID groups (HE, original magnification x 400).
Photomicrographs of WT and Placebo-control groups were obtained from a previous study [10].
Fig 3.
Histomorphometric analysis of all experimental groups.
The aaa indicates a significant difference compared with Placebo-control group (p<0.001), aaaa indicates a significant difference compared with Placebo-control group (p<0.0001), b indicates a significant difference compared with WT group (p<0.05), bb indicates a significant difference compared with WT group (p<0.01), bbbb indicates a significant difference compared with WT group (p<0.0001),), c indicates a significant difference compared with NSAID group (p<0.05), ccc indicates a significant difference compared with NSAID group (p<0.001), cccc indicates a significant difference compared with NSAID group (p<0.0001), ddd indicates a significant difference compared with PBMT + Prednisone group (p<0.001), dddd indicates a significant difference compared with PBMT + Prednisone group (p<0.0001), eeee indicates a significant difference compared with Prednisone group (p<0.0001), and ffff indicates a significant difference compared with PBMT + NSAID group (p<0.0001).
Fig 4.
Protein expression of dystrophin in all experimental groups.
The *** indicates a significant difference compared with WT group (p<0.001), **** indicates a significant difference compared with WT group (p<0.0001), ### indicates a significant difference compared with placebo group (p<0.001), #### indicates a significant difference compared with placebo group (p<0.0001), and ϕϕϕϕ indicates a significant difference compared with NSAID group (p<0.0001); n = 5 animals per group.
Fig 5.
Functional performance assessment performed at baseline and post-treatment timepoints.
The * indicates a significant difference compared with all experimental groups at baseline (p<0.05), ** indicates a significant difference compared to placebo-control group at post-treatment evaluation (p<0.01), and **** indicates a significant difference compared with all experimental groups at baseline, and all the other experimental groups at post-treatment evaluation (p<0.0001); n = 5 animals per group.