Fig 1.
Study population flowchart.
Table 1.
Demographic and clinical characteristics of the subjects.
Fig 2.
Preprocessing steps of the rCBF maps.
Fig 3.
Statistical nonparametric T map of rCBF reduction in the OCD patients vs. healthy controls.
(A) The three orthogonal planes represent a maximum intensity projection (MIP) ‘glass brain’. (B–D) Selected planes show results superimposed on MNI152 T1 template. Color bar: Student’s T-values. Significant reductions of rCBF are observed in the right putamen (black arrow), right frontal operculum (black arrowhead), left midcingulate cortex (white arrow), and right temporal pole (white arrowhead) in the OCD patients compared to the controls (thresholded at T > 3.93, p<0.05 with the family-wise error rate correction for multiple comparisons in the SnPM analysis). There were no areas of increased rCBF in the OCD patients (data not shown). rCBF, regional cerebral blood flow; OCD, obsessive-compulsive disorder; SnPM, statistical nonparametric mapping.
Table 2.
Regions showing decreased rCBF in the OCD patients compared to the healthy controls.