Fig 1.
Semantic storage loss calculation.
Table 1.
Core criteria used for classifying PPA sub-types.
Table 2.
Naming and neuropsychology data for PPA participants.
Fig 2.
FDG PET results for the three PPA participant groups.
Differences in cerebellar gray-relative FDG ratios, calculated per vertex, superimposed onto an averaged, elderly cortical surface. Images are thresholded such that only ratio differences greater than 0.1 are mapped to the spectral color bar. (Top row) Areas in which the nfvPPA group demonstrated a larger magnitude FDG ratio, when compared to the average of the svPPA and lfPPA groups. (Middle row) Comparison of lvPPA group FDG ratios against the averaged svPPA and nfvPPA groups, and (Bottom row) comparison of svPPA group ratios against the averaged nfvPPA and lvPPA groups.
Fig 3.
Bar graphs comparing the average semantic storage loss score found for each PPA group.
Consistent with the prediction that semantic storage loss scores would be indicative of temporal, rather than frontal lobe damage, those participants in the svPPA group had the lowest SSL scores.
Fig 4.
Scatterplots display the relationship found between participants’ semantic loss scores and their found metabolism ratio in different brain areas.
Although semantic store loss scores are poor predictors of dorsolateral frontal lobe metabolism levels, they predicted metabolism levels in the left and right ATL.
Table 3.
Predicting ATL hypometabolism in PPA participants.