Table 1.
Direct antimutagenic activities of F. angustifolia Vahl.
Antimutagenic activities of F. angustifolia Vahl. leaves and stem bark extracts on TA98 and TA100 strains after 72h co-incubation with direct mutagens, respectively 2-NF (2.5 and 5 μg/mL) and NaN3 (5 and 10 μg/mL), in the absence of metabolic activation system S9.
Table 2.
Indirect antimutagenic effects of F. angustifolia Vahl.
Antimutagenic effects of F. angustifolia Vahl. leaves and stem bark extracts on strains TA98 and TA100 after 72h co-incubation with indirect mutagens, respectively 3-MC (25 and 50 μg/mL) and CP (50 and 100 μg/mL), in presence of metabolic activation system S9.
Table 3.
Antigenotoxicity of F. angustifolia Vahl.
Antigenotoxicity of F. angustifolia Vahl. leaves and stem bark extracts (25, 50, 100 μg/mL) after 2h co-incubation with standard genotoxins: 4-NQO 0.05μg/mL and 2-AA 0.20μg/mL, respectively for the treatment in absence and in presence of metabolic activation S9.
Table 4.
IC50 values (μg/mL), with 95% confidence range (in brackets) obtained by MTT assay after 72h treatment of Hep-G2 and MCF7 cell lines with leaves and stem bark extracts of F.angustifolia Vahl.
Table 5.
Extraction yield and quantitative phytochemicals screening.
Extraction yield and quantitative phytochemicals screening of extracts from F. angustifolia Vahl.
Fig 1.
HPLC chromatogram (254 nm) of the composition of the aqueous chloroform (FL5) extract and its native crude extract (FL1) of F. angustifolia Vahl leaves. FL1: Ethanolic extract; FL5: aqueous/ chloroform extract.
Table 6.
Retention times (tr) of the ions (m/z) and the molecular weights.
Table of the retention times (tr) of the ions (m/z) and the molecular weights corresponding to the peaks revealed in the HPLC/MS spectra of F. angustifolia Vahl. leaves extracts.
Fig 2.
HPLC chromatogram (254 nm) of the composition of the aqueous chloroform (FSB5) extract and its native crude extract (FSB1) of F. angustifolia Vahl stem bark. FB1 ethanolic extract; FB5 aqueous/ chloroform extract.
Table 7.
Retention times (tr) of the ions (m/z) and the molecular weights.
Table of the retention times (tr) of the ions (m/z) and the molecular weights corresponding to the peaks revealed in the HPLC/MS spectra of F. angustifolia Vahl. stem bark extracts.