Fig 1.
Flowchart to outline the details of the recruitment process of patients with encephalitis into the short- and medium-term and long-term outcome cohorts, and of healthy controls.
Table 1.
Demographic characteristics of patients and controls in the short- and medium-term outcome cohort as well as patients and controls in the long-term outcome cohort.
Table 2.
Short-term neuropsychological and psychiatric assessment scores in the short- and medium-term outcome cohort.
Fig 2.
Mean anterograde memory scores for each aetiological group (Doors & People test).
The error bars represent the standard deviation of the mean score within each group. (a) At the short-term assessment, a mean of 4 months post-discharge (in the short- and medium-term outcome cohort) and (b) at the long-term assessment, at least 1 year post-discharge (in the long-term outcome cohort). Notations: *p≤0.05, **p≤0.01; † Hochberg GT2/Games-Howell post hoc (parametric); ▪Bonferroni-corrected pairwise analysis (ANCOVA post hoc). ◊ Mann Whitney U post hoc (non-parametric).
Fig 3.
Subjective cognitive complaints for each group (ABNAS subscale scores).
The error bars represent the standard deviation of the mean score within each group. (a) At the short-term assessment, a mean of 4 months post-discharge (in the short- and medium-term outcome cohort) and (b) at the long-term assessment, at least 1-year post-discharge (in the long-term outcome cohort). Notations: For main analyses of subscales (all Kruskal Wallis), significance is labelled adjacent to the subscale name along the x-axis, alpha p = 0.05, * p ≤ 0.05, ** p ≤ 0.01; For the breakdown of main analyses using Mann Whitney U post hoc, significance is labelled adjacent to data points within the figure, corrected alpha p = 0.02, * p ≤ 0.02, ** p ≤ 0.01, ^ trending significance (p = 0.03); Abbreviations: ABNAS (A-B Neuropsychological Assessment Schedule).
Table 3.
The significant correlations between clinical variables and short-term neuropsychological assessment scores in the short- and medium-term outcome cohort.
Table 4.
Prevalence (%) of damage across brain regions in each encephalitis group on MRI.
Table 5.
The relationship between MRI findings and short-term neuropsychological outcomes.
Table 6.
Long-term neuropsychological and psychiatric assessment scores in the long-term outcome cohort.