Table 1.
Clinical and pathological characteristics of the 49 patients with poorly differentiated thyroid cancer at the presentation stage.
Fig 1.
Poorly differentiated thyroid cancer (PDTC) in H&E stain.
(A) PDTC with predominant solid growth pattern with atypical mitosis (×400), (B) trabecular pattern of growth (×200), and (C) insular pattern of growth with necrosis (×200).
Fig 2.
Histological findings (H&E stain) in poorly differentiated thyroid cancer.
(A) Atypical mitosis in a tumor with a predominant insular pattern of growth (×400), and (B) extensive necrosis (×200). Thyroglobulin immunohistochemistry: (C) positive and (D) negative.
Table 2.
Immunohistochemistry in poorly differentiated thyroid cancer (n = 48).
Fig 3.
Kaplan-Meier analysis of disease-specific survival in patients with poorly differentiated thyroid cancer.
According to (A) tumor size, (B) presence of atypical mitoses, (C) thyroglobulin-negative immunostaining, and (D) Ki-67 >5%.
Table 3.
Predictive factors of disease-specific survival in PDTC patients.
Table 4.
The presence of atypical mitoses as a predictive factor of DSS in PDTC patients with an insular (n = 34), and a predominant (>50%) insular (n = 30), pattern of growth.
Table 5.
Multivariate analysis of DSS in PDTC patients performed using the Cox proportional-hazards model.