Table 1.
List of significantly altered taxa with a relative abundance of at least 0.005% between the CO and KO groups at all taxonomic levels.
Statistical significance was tested using Welch’s t-test with the confidence interval threshold of 95% and p<0.05.
Fig 1.
Principal component analysis (PCA) plot of the functional profiles of CO and KO groups at (A) level 1, (B) level 2, and (C) level 3 of EggNOG. Each dot represents a sample and the distinct color represents the type of the sample. The percent variability explained by each principal component is shown in parentheses in the axes legends.
Table 2.
List of selected significantly altered functions in the CO and KO groups which might be involved directly and indirectly in the progression of colitis.
The confidence interval threshold was 95% and p<0.05. Dark grey color indicates the abundance of a particular function is increasing and light grey color indicates the abundance of a particular function is decreasing.
Table 3.
Details of genes associated with sulfur reduction II (via polysulfide) and sulfate reduction I (assimilatory) pathways found in Desulfovibrio sp. 3_1_syn3 and Nitrobacter sp. Nb-311A, respectively.