Table 1.
Demographic and clinical characteristics of IMD patients between 2009 and 2015 in Germany.
Fig 1.
Mean overall costs in Euro (€) of IMD cases within pre-defined follow-up periods after diagnosis and stratified by clinical presentation of IMD.
IMD = Invasive meningococcal disease; Data for other IMD in the time period 5 to 7 years could not be displayed due to data protection reasons (n<5); further information on SD and costs by clinical presentation of IMD in each healthcare sector is available in S2 Appendix.
Table 2.
Adjusted ratio of length of stay of IMD-related index hospitalization (2009–2015).
Table 3.
Adjusted cost ratios of total costs per day during IMD-related index hospitalization (2009–2015).
Table 4.
Adjusted cost ratios of total cost per day during the overall follow up period after discharge from IMD-related index hospitalization for all IMD patients.
Table 5.
Rate ratios of healthcare resource utilization during the study follow-up period (IMD cases vs. matched controls, 2009–2015).
Fig 2.
Mean costs (in Euro = €) of IMD cases and matched controls without IMD within pre-defined follow-up periods after IMD diagnosis, overall and stratified by healthcare sector.
* statistically significant at bootstrap p-value <0.05 obtained from two-part regression model composed of a logistic regression model in all patients with an indicator of non-zero costs as dependent variable, and a gamma regression model in patients with costs greater zero with costs as dependent variable; IMD = Invasive meningococcal disease; based on data from n = 147 IMD cases and n = 567 matched controls without IMD.
Table 6.
Adjusted cost ratios of healthcare resource utilization during the study follow-up period (IMD cases vs. matched controls, 2009–2015).