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Fig 1.

Properties of iAM957.

(a) distribution of the metabolic reactions in the categories. (b) number of non-gene associated (red) and gene associated (blue) reactions in each category.

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Table 1.

Features of the metabolic model reconstructed for A. variabilis ATCC29413 in comparison with metabolic models of other cyanobacteria.

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Table 2.

The Pearson correlation between the predicted and measured relative growth rates on various carbon sources for the two single-cell models.

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Fig 2.

Comparison of growth rates predicted by the two-cell models and the regulated two-cell model with experimental data [63].

The labeled values indicate irradiance (lux) and bicarbnate uptake rate (mmol/gDCW/h), respectively, for each data. The same colors were used for distant points with the same experimental data.

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Fig 3.

Double robustness analysis using the regulated two-cell model for photoautotrophic growth of Anabaena variabilis.

The heatmap presents changes in the growth rate with varying oxygen exchange and hydrogen production fluxes in a) vegetative and b) heterocyst cells.

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Fig 4.

The predicted flux distributions for minimal (top) and maximal (down) hydrogen production under a constant growth rate.

Abbreviations of metabolites are available in S1 File.

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