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Table 1.

Summary characteristics of women with singleton and twin pregnancy by gestation group.

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Table 1 Expand

Table 2.

Number of sequence reads per sample and percentage alignment to Tophat2.

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Table 2 Expand

Fig 1.

Principal component analysis (PCA) of the 1st and 2nd principal components from the 4 groups.

Singleton Preterm (blue), Singleton Term (red), Twin Preterm (green), Twin Term (black). PCA was performed using the log10 count data from all libraries.

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Fig 1 Expand

Fig 2.

Sample correlation heat map of the correlation of all libraries.

Each diagonal block (bottom left to top right) on the plot shows the correlation of samples within a sample group. Each of the remaining blocks shows the correlation between sample groups. SP; Singleton preterm, SP; Singleton term, TP; Twin preterm, TT; Twin term.

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Fig 2 Expand

Table 3.

Numbers of DEGs identified in each contrast.

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Table 3 Expand

Fig 3.

Heat map of log fold count (LogFC) of DE genes in the 4 contrasts.

Detected DE genes were clustered based on the logFC value from all contrasts using the k-means method. SP; Singleton preterm, SP; Singleton term, TP; Twin preterm, TT; Twin term.

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Fig 3 Expand

Table 4.

Protein coding transcripts up-regulated in term twin myometrium versus preterm singleton myometrium.

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Table 4 Expand

Table 5.

Protein coding transcripts down-regulated in term twin myometrium versus singleton preterm myometrium.

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Table 6.

Significant Gene Ontology terms identified for biological processes in twin term myometrium compared to singleton preterm myometrium.

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Table 7.

Significant Gene Ontology terms identified for molecular function in twin term myometrium compared to singleton preterm myometrium.

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Table 8.

Significant Gene Ontology terms identified for cellular component in twin term myometrium compared to singleton preterm myometrium.

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Table 8 Expand

Table 9.

Significant KEGG pathways identified in twin term myometrium compared to singleton preterm myometrium.

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