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Table 1.

Selected characteristics of the study cohort.

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Table 2.

Proportion of patients who underwent clinical procedures and received treatment in line with pre-defined standards.

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Table 3.

Linear regression for factors associated with delay in antibiotic treatment.

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Fig 1.

Distribution of patients according to number of non-completed or delayed key diagnostic procedures.

Key procedures: triage within 15 minutes, examination by physician in accordance with urgency specified during triage, blood lactate measured within 1 hour, adequate observation regimen. N = 1559.

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Fig 2.

All-cause 30-day mortality by time to antibiotic treatment.

Gray shaded histogram represents mortality rates according to time to antibiotic treatment in hours. Solid black curve with bars represents model-predicted mortality rates with 95% confidence intervals according to time to antibiotic treatment in minutes using logistic regression models, adjusted for patient’s age, date of admission, comorbidity, and presence of organ failure. Date of admission was measured using calendar days since study start, entered as a polynomial function with first (b -0.011 p<0.001), second (b 2.5e-5 p<0.001) and third degree (b -1.2e-8 p<0.01) variables. The model prediction uses average values for adjustment values.

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