Fig 1.
Representative right eye images of a typical RP patient, visual acuity 20/13.
A: Fundus photo. B: FAF. C: OCT; “TRT” refers to the thickness between the ILM and the RPE. “ORT” refers to the thickness from OPL to RPE. D-E. Co-registered images of fundus photo, microperimetry results, and the ORT/TRT thickness map. The color of the point indicates the retinal sensitivity, and the color of the background indicates the retinal thickness. Regarding the retinal sensitivity, green indicates high and red indicates low retinal sensitivity. Regarding the retinal thickness, green indicates thick and blue indicates thin. (D: TRT, E: ORT).
Fig 2.
Representative right eye images of a typical RP patient, visual acuity 20/16.
A: Fundus photo. B: FAF. C: OCT. D-E. Co-registered images of fundus photo, microperimetry results, and the ORT/TRT thickness map. (D: TRT, E: ORT).
Table 1.
Characteristics of the 30 patients with retinitis pigmentosa.
Table 2.
Clinical characteristics of RP patients.
Fig 3.
Correlation analysis between the retinal sensitivity and the TRT/ORT.
A-B: This figure shows the rank correlation coefficients between the retinal sensitivity and the retinal thickness at each test point (A: TRT, B: ORT). The points of statistically significant correlation (p<0.05) were outlined in bright red. The intensity of the red dots indicates the strength of the correlation between the retinal sensitivity and the retinal thickness. The correlations were analyzed by the non-parametric Spearman test. C-D: Rank correlation coefficients of 40 points were divided into four zones according to the retinal eccentricity and the difference of correlation coefficients between 2°–6° and 8° was analyzed using the Wilcoxon rank sum test (**p<0.01) (C: TRT, D: ORT). E: The rank correlation coefficients between the retinal sensitivity and the ORT was compared with those between the retinal sensitivity and the TRT at each test point. The dot color indicates the distance from the fovea (orange: 2°, light blue: 4°, green: 6°, purple: 8°). The difference of correlation coefficients between two groups was analyzed using the Wilcoxon rank sum test (*p<0.05).
Fig 4.
The scatter-plot analysis of the relationships between TRT/ORT and retinal sensitivity at each retinal eccentricity.
The scatter-plots showing the relationships between the TRT/ORT and the corresponding the retinal sensitivity measured by MP-3 at 2°, 4°, 6°, and 8° eccentricity.