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Fig 1.

Clinical presentation of homogeneous leukoplakia.

(A) and non-homogeneous leukoplakia (B) in the buccal mucosa.

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Fig 2.

ORA-LEU-CAN study flow chart.

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Table 1.

Patients’ characteristics.

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Table 1 Expand

Fig 3.

Clinical appearances of three patients and the definition of a recurrence of leukoplakia.

Patient 1: A, B, C; 2: A, B, C; 3: A, B, C. A clinical healthy mucosa had to be recorded with a clinical photograph between the time of surgery and the time of recurrence.

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Table 2.

Patients treated with surgical removal of leukoplakia.

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Table 2 Expand

Fig 4.

Kaplan-Meier curves for disease-free survival of patients with OL.

Time shown is years from excision to recurrence. (A) Clinical diagnosis: P = 0.021; (B) Size: P = 0.445; (C) Dysplasia: P = 0.166; (D) Number of lesions: P = 0.587; (E) Smokers: P = 0.216; (F) Snuff users: P = 0.003.

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Fig 4 Expand

Table 3.

Cox regression analysis of risk factors for the recurrence of OL.

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Table 3 Expand