Fig 1.
Flow diagram showing the selection for the enrolled patients with nonarteritic anterior ischemic optic neuropathy.
The controls included individuals who had attended Seoul National University Hospital Healthcare System, Gangnam Center for routine health screening. SNUBH: Seoul National University Bundang Hospital; NAION: nonarteritic anterior ischemic optic neuropathy; MRI: magnetic resonance imaging.
Fig 2.
Cerebral small vessel disease in a patient with NAION.
(A) A case of NAION with hyperemic disc, segmental swelling, and disc hemorrhage in a 62-year-old woman. (B) White matter hyperintensities (Fazekas grade 3) on brain MRI (FLAIR image: white asterisks). (C) Cerebral microbleeds on T2-weighted brain MRI (white arrowhead) (D) silent lacunar infarct on T1-weighted MRI (white arrow) corresponding to cerebral small vessel disease. NAION: nonarteritic anterior ischemic optic neuropathy; MRI: magnetic resonance imaging; FLAIR: fluid attenuated inversion recovery.
Table 1.
Demographics and brain MRI findings of patients with NAION and controls before and after adjusting with SMR.
Table 2.
Multivariate logistic regression results for small vessel disease before SMR adjustment.
Table 3.
Multivariate logistic regression results for small vessel disease after SMR adjustment.