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Fig 1.

Pathway for contingent non-invasive prenatal testing strategy.

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Fig 2.

Pathway for diagnostic testing.

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Fig 3.

Pathway for serum-only screening strategy without non-invasive prenatal testing.

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Fig 4.

Pathway for universal non-invasive prenatal testing strategy.

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Table 1.

Model inputs.

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Table 1 Expand

Fig 5.

Cost-effectiveness acceptability curve–base case.

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Fig 5 Expand

Table 2.

Base case results at population level.*

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Table 2 Expand

Table 3.

Results of scenario analyses.

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Table 3 Expand

Fig 6.

Cost-effectiveness acceptability curve–cost of non-invasive prenatal testing at $200.

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Fig 6 Expand