Table 1.
The model parameter ranges used in Sobol’s method.
Fig 1.
Predicted dengue importations for August 2015.
The map shows the output of our model for August 2015.The area of a node increases with the number of dengue cases imported through the corresponding airport. Airports that are predicted to not receive any infections are not shown on the map. Endemic countries are coloured dark grey. Countries that are non-endemic and where dengue vectors Aedes aegypti and/or Aedes albopictus are present are coloured in light grey. The blue circles correspond to the top ten airports identified in Fig 2. The map was created with the Python GeoPandas package and publicly available shapefiles from Natural Earth (http://www.naturalearthdata.com/).
Fig 2.
Predicted monthly dengue importations by airport for 2015.
The number of predicted imported dengue infections for the top ten airports in non-endemic countries/states with vector presence for each month in 2015. A break in a line indicates that the corresponding airport was not amongst the top ten during the respective month. Airports are abbreviated using the corresponding IATA code. A full list of abbreviations can be found in the supplementary material (see Table A in S1 File).
Table 2.
The ten routes with the highest predicted number of dengue-infected passengers with final destinations in non-endemic countries with vector presence.
Fig 3.
Predicted dengue infections imported by returning residents and visitors in 2015.
Here we show the results for non-endemic countries/states with vector presence with the highest number of predicted imported dengue cases in 2015. The bars are stacked to distinguish between returning residents (green) and visitors (blue). The blue solid line corresponds to the total number of imported cases. The error bars correspond to the model’s coefficient of variation (see Material and methods). The six countries were selected because they are predicted to receive the highest number of dengue importations, are non-endemic and dengue vectors are established.
Fig 4.
Predicted percentage contribution of dengue importations by country of acquisition in 2015.
The predicted percentage contribution by source country and month in 2015. The size and colour of the circles indicate the percentage contribution of the corresponding country to the total number of imported cases. The y-labels indicate the yearly percentage contribution of the corresponding source country.
Fig 5.
Rank-based validation and correlation between reported and predicted imported cases for Queensland in 2015.
(A) Countries are ranked by the total number of predicted and reported imported dengue cases. The reported ranking is then plotted against the predicted ranking. Countries that were ranked by the model, but did not appear in the dataset receive a rank of i + 1, were i is the number of unique importation sources according to the dengue case data. Similarly, countries that appeared in the data and were not ranked by the model receive a rank of i + 1. For circles that lie on the x = y line (grey solid line) the predicted and reported rankings are equal. Circles that lie between the two dashed lines correspond to countries with a difference in ranking that is less than or equal to five. The circle areas are scaled proportionally to the number of reported cases that were imported from the corresponding country. Spearman’s rank correlation coefficient between the absolute numbers of reported and predicted importations is equal to 0.6. (B) The absolute number of reported dengue importations are plotted against the absolute number of predicted importations.
Table 3.
Yearly and seasonal reporting rates of imported cases in 2015.