Table 1.
Demographic, anthropometric and disease specific characteristics in adults and children with Friedreich ataxia.
Fig 1.
Box and whisker plots of left ventricular structural variables.
Box and whisker plots for subjects with Friedreich ataxia who were homozygous for GAA repeat expansions, had GAA measurements performed in our laboratory, and had sinus rhythm and a LVEF >50%, showing LVEDID indexed to BSA (A), SWT (B), RWT (C), LV mass indexed to BSA (D) and LV mass indexed to height2.7 (E). Children and adults are shown separately for all variables, and males and females are shown separately for variables in which male sex was associated with larger variable size independent of BSA. See Table 2 for abbreviations.
Table 2.
Left ventricular and transmitral Doppler variables in children and adults with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF.
Table 3.
Univariate correlations (r) of left ventricular structural variables in children with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF (n = 60).
Table 4.
Multivariate models of left ventricular structural variables in children with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF (n = 60).
Table 5.
Univariate correlations of left ventricular structural variables in adults with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF (n = 124).
Table 6.
Multivariate models of left ventricular structural variables in adults with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF (n = 124).
Table 7.
Multivariate models of LVEDID, LVEDL and LVEDV in combined group of children and adults with FRDA who were homozygous for GAA repeat expansions and had a normal LVEF (n = 184).