Fig 1.
The schema of whole-pancreatic analysis and representative fat-water MRI images of low or high degree of pancreatic steatosis.
(A) The schema of whole-pancreatic analysis is shown. (B) Representative pancreatic images of fat-water MRI are shown. A white arrow indicates the pancreas. The left panel shows the low degree of pancreatic steatosis in a sample whose whole-pancreatic FF value was determined to be 1.20%. The right panel shows the high degree of pancreatic steatosis in a sample whose whole-pancreatic FF value was determined to be 34.87%.
Fig 2.
Evaluation of reproducibility of each measurement method.
(A) The representative result of the evaluation of the variations in values of hepatic or pancreatic PDFF depending on the positions of the ROIs is shown. The values of the pancreatic PDFF measured using small ROIs varied widely depending on the locations of the ROIs. (B) All measurements by observer #1 for intra-observer variability analysis are shown. (C) All measurements by 6 observers for inter-observer variability analysis are shown. The average value of five repeated measurements by each observer was taken as the measured value of the observer.
Table 1.
Clinical, serologic and histologic characteristics of the subjects.
Table 2.
Correlation between whole-pancreatic PDFF and the clinical characteristics.
Fig 3.
Correlation between whole-pancreatic PDFF and the clinical characteristics.
Whole-pancreatic FF was correlated with age (left panel, p = 0.039), BMI (middle panel, p = 0.0093), and presence/absence of diabetes (right panel, p = 0.0055).
Table 3.
Identified factors which were correlated with the degree of pancreatic steatosis by multiple logistic regression analysis.
Fig 4.
Correlation between whole-pancreatic PDFF and the hepatic PDFF or NAS score.
Whole-pancreatic PDFF was not correlated with hepatic PDFF (left panel, p = 0.76), and NAS score (right panel, p = 0.29). (B) Head-PDFF was not correlated with hepatic PDFF (left panel, p = 0.29), and NAS score (right panel, p = 0.25). (C) Body-tail PDFF was not correlated with hepatic PDFF (left panel, p = 0.87), and NAS score (right panel, p = 0.42).