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Fig 1.

Methods for calculating VD, BFA, and FAZ from en face OCTA images.

All images are from the same eye of a single subject. (A, B) En face OCTA images representing the VD calculated with the annulus automatically centered at the level of the SCP (A) and DCP (B). (C, D) Measurement of FAZ in the SCP (C) and DCP (D) using built-in software with OCTA AngioAnalytics. (E-G) En face OCTA images representing the areas (shaded in yellow) selected to measure the BFA in the choriocapillaris in the region below the 3x3mm macular area (E), central 1mm circular area of the fovea (F), and parafovea (G). VD = vessel density (%), SCP = superficial capillary plexus, DCP = deep capillary plexus, BFA = blood flow area (%), FAZ = foveal avascular zone (mm2).

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Fig 1 Expand

Table 1.

Characteristics of the subject groups.

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Table 1 Expand

Fig 2.

Representative maps of mean VD (A-D) and FAZ (E) in the SCP and DCP, and BFA (F) in the choriocapillaris for both subject groups. Data are presented as means ± standard deviation. Portions of the map shaded in gray represent areas where there was a statistically significant difference between the two subject groups. Maps representing the VD in the 3x3mm area of the macular image (A), parafovea and fovea (B), superior and inferior hemifields (C), and parafoveal quadrants (D). Maps representing the area of FAZ in the SCP and DCP (E). VD = vessel density (%), FAZ = foveal avascular zone (mm2), BFA = blood flow area (%), SCP = superficial capillary plexus, DCP = deep capillary plexus, S-H = superior hemifield, I-H = inferior hemifield, S = superior, N = nasal, I = inferior, T = temporal. *p<0.05, linear mixed models. See Table 1 for corresponding p values.

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Fig 2 Expand

Table 2.

VD, BFA, and FAZ in the SCP, DCP, and choriocapillaris for black and white subject groups.

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Table 2 Expand