Fig 1.
Schematic overview of the HF classification scheme.
Table presents age and sex distribution of individuals with HF belonging to the various subphenotyping bins.
Table 1.
FHS criteria for a heart failure diagnosis.
Table 2.
Characteristics of participants without overt HF (sample 1).
Table 3.
Association between subphenotypes and various echocardiographic and arterial stiffness measures in individuals without overt HF (sample 1).
Table 4.
Characteristics of individuals with HFrEF according to subphenotype category (N = 465).
Table 5.
Characteristics of individuals with HFpEF according to subphenotype category (N = 372).
Table 6.
Age and sex adjusted 10-year mortality by group.
Fig 2.
Hazards ratio associated with various subphenotypes for all-cause mortality.
Panel A refers to the results from a Cox model including only HFrEF patients, the CHD subgroup served as the referent. Similar, panel B illustrates to the results from a sub-analysis including only HFpEF patients. The panel C shows within each subgroup comparison of mortality risk in HFpEF vs. HFrEF.
Fig 3.
Hazards ratio associated with various subphenotypes for cardiovascular mortality.
Panel A refers to the results from a Cox model including only HFrEF patients, the CHD subgroup served as the referent. Similar, panel B illustrates to the results from a sub-analysis including only HFpEF patients. The panel C shows within each subgroup comparison of mortality risk in HFpEF vs. HFrEF.