Fig 1.
Flow diagram patient's inclusion.
Fig 2.
OCT report of retinal thickness analysis.
(A) Concentric macular rings and four peripapillary quadrants (B) Rectangular grid 6x6 macular sectors and peripapillary thickness for each 12-o’clock hour and (C) Macular thickness segmentation of 10 retinal layers.
Fig 3.
Median data of the psychophysical tests.
(A) Visual acuity, (B) contrast sensitivity, (C) desaturated Rue 28-hue color test, and (D) perception digital test. Each bar represents the median ± interquartile range. * P < 0.05 versus control. ** P < 0.01 versus control. Mann-Whitney U test.
Table 1.
Median data and p-value of the psychophysical tests.
Fig 4.
Colorimetric percentage differences of retinal thickness between groups.
(A) Macular OCT. Upper: OCT concentric circular rings. Bottom: 6x6 mm rectangular grid, (B) Peripapillary OCT. Upper: Four peripapillary quadrants. Bottom: 12-o’clock hour position segmentation. In red, thickness decrease; in green thickening. In bold: *P < 0.05. **P < 0.01. Mann-Whitney U test.
Table 2.
aROC analysis of psychophysical tests and OCT analysis in Alzheimer’s disease.
Fig 5.
Colorimetric percentage differences of the all retinal layers between mild AD and control group.
In red, thickness decrease; in green thickening. *P < 0.05. **P < 0.01. Mann-Whitney U test.