Fig 1.
Flow diagram of Recall (A) and Reflex (B) DNA screening.
Table 1.
Input unit cost estimates*.
Table 2.
Input test performance and uptake estimates according to Combined test markers risk cut-off.
For derivation of values see S1 Fig.
Table 3.
Comparison of efficacy and costs of recall and reflex DNA screening according to Combined test markers risk cut-off and cost of the DNA analysis.
Fig 2.
Cost per affected pregnancy (trisomy 21, 18 or 13) diagnosed according to the combined test markers risk cut-off used to select women for a DNA analysis for recall and reflex DNA screening and DNA analysis costs of £250 and £100.