Table 1.
Demographic and clinical characteristics of participants.
Fig 1.
Lesion overlay maps of LHD and RHD patients of the Subacute (n = 65, n = 65; respectively), Chronic (n = 34, n = 32; respectively) and Delta (n = 25, n = 24; respectively) groups.
T = threshold for inclusion in the VLSM analysis: at least 20% of the subjects had to have damage to a particular voxel for it to be included in the analysis. Regions analyzed in each of the 6 figures are those coded by colors above the T mark. Representative normalized slices (out of 90 normalized slices employed) are displayed in radiological convention (right hemisphere on left side and vice versa), with warmer colors indicating greater lesion overlap (units: number of patients with lesion in this region).
Fig 2.
VLSM analysis depicting areas of damage that were associated with lower FM A, B+C, T and B&B scores in the LHD (A) and RHD (B) groups during the subacute phase. Colored regions denote voxels where damage exerted a significant impact on behavioral scores, based on a lenient criterion of z score = 2.00 (p = 0.01) or above in the LHD group (all clinical assessment scales) and B&B of the RHD group. The colored regions in FM A, B+C, T of the RHD group survived FDR correction for multiple comparisons. Voxels were analyzed only if they were damaged in at least 20% of the sampled stroke patients. Significant voxels are reported only if they are part of clusters comprising at least 10 voxels. Regions in red correspond to higher z scores.
Fig 3.
VLSM analysis depicting areas of damage that were associated with lower FM A, B+C, T and B&B scores in the LHD (A) and RHD (B) groups during the chronic phase. Colored regions denote voxels where damage exerted a significant impact on behavioral scores, based on a lenient criterion of z score = 2.00 (p = 0.01) or above in the LHD group (all clinical assessment scales), and FDR correction for multiple comparisons in the RHD group (all clinical assessment scales). Voxels were analyzed only if they were damaged in at least 20% of the sampled stroke patients. Significant voxels are reported only if they are part of clusters comprising at least 10 voxels. Regions in red correspond to higher z scores.
Fig 4.
VLSM analysis depicting areas of damage that were associated with lower B&B gain in the LHD group (A) and lower FM B+C and FM T gains in the RHD group (B) in the time interval between the subacute- and chronic-phase examinations. Colored regions denote voxels where damage exerted a significant impact on behavioral scores, based on a lenient criterion of z score = 2.00 (p = 0.01) or above in the LHD and RHD groups. Voxels were analyzed only if they were damaged in at least 20% of the sampled stroke patients. Significant voxels are reported only if they are part of clusters comprising at least 10 voxels. Regions in red correspond to higher z scores.
Table 2.
VLSM results in LHD patients (n = 65) at the subacute phase.
Table 3.
VLSM results in RHD patients (n = 65) at the subacute phase.
Table 4.
VLSM results in LHD patients (n = 34) at the chronic phase.
Table 5.
VLSM results in RHD patients (n = 32) at the chronic phase.
Table 6.
VLSM results in LHD patients (n = 25) of the Delta group.
Table 7.
VLSM results in RHD patients (n = 24) of the Delta group.