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Fig 1.

The photograph of inner surface and the SEM images of cross-section of P. viridis shell.

A: the photograph of inner surface of an adult P. viridis shell. The black dot line represents the cutting plane; “AMS-A”, “AMS”, and “AMS-P” represent the area of anterior side from adductor muscle scar (AMS), central AMS, and the posterior side from AMS, respectively. B: the SEM image of the section of AMS-A. N represents the nacre layer, M represents the myostracum layer; C: the SEM image of the section of central AMS; D: the SEM image of the section of AMS-P. E: the SEM image of the section close to the outside of the shell; F: the SEM image of the section of the outside of the shell. The bar is 10 μm for B, C, D, and E, and 20 μm for F.

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Fig 2.

Surface images of AMS and AMS-A region.

A: the inner surface image of natural shell of P. viridis at AMS region with the adductor muscle attached; B: the SEM image of surface of AMS region after the adductor muscle removed. The pit structures are denoted by arrows; C: the SEM image of the surface from transition zone between the AMS and AMS-A; D: the SEM image of the surface of AMS-A; E: The SEM image of the AMS surface after deproteinization; F: The SEM image of the AMS-A surface after deproteinization.

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Fig 3.

FTIR spectra and XRD profiles of the nacre layer and myostracum layer.

A: FTIR spectra of the two layers of P. viridis shell. The single star and the double star indicate the amide I and amide II region, respectively. B: XRD profiles of the two layers of P. viridis shell. The arrows represent the aragonite peaks.

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Fig 4.

SEM images of shell cross-section at AMS-A and AMS of P. viridis after collagenases digestion.

A: the section image of AMS-A from the control sample; B: the section image of AMS from the control sample; C: the SEM image of AMS–A section after type-I collagenase digestion; the etched cracks and holes can be seen at the tablet of the nacre layer; D: the SEM image of AMS section after type-I collagenase digestion; the etched area at the myostracum layer are denoted by black arrows; E: the section image of AMS-A from the control sample; F: the section image of AMS from the control sample; G: the SEM image of AMS–A section after type-II collagenase digestion; the etched area at the nacre layer are circled with white dash line and the etched crack of the myostracum layer are denoted by black arrows; H: the SEM image of AMS section after type-II collagenase digestion; the etched area at the nacre layer are denoted by black arrows. The bar is 5 μm.

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Fig 5.

SEM images of shell cross-section at AMS-A and AMS of P. viridis after chitinases digestion.

A: the section image of AMS-A from the control sample; B: the section image of AMS from the control sample; C: the SEM image of AMS–A section after chitinase digestion; the etched long cracks at the nacre layer are denoted by arrows; D: the SEM image of AMS section after chitinase digestion; the etched long cracks at the nacre layer are denoted by arrows. E: the section image of AMS-A from the control sample; F: the section image of AMS from the control sample; G: the SEM image of AMS–A section after chitinase digestion; the etched long cracks at the nacre layer are denoted by arrows; H: the SEM image of AMS section after chitinase digestion; the etched long cracks at the nacre layer are denoted by arrows. The bar is 5 μm for A, B, E, F and G, and 10 μm for C, D, and H, respectively.

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Fig 6.

SEM images of inner surface at the AMS-A and the AMS area after enzyme digestion.

A: the surface image of AMS-A from control sample; B: the surface image of AMS from control sample; C: the SEM image of AMS–A surface after collagenase digestion; D: the SEM image of AMS surface after collagenase digestion; E: the SEM image of AMS–A surface after chitinase digestion; F: the SEM image of AMS surface after chitinase digestion.

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Fig 7.

Gene Ontology annotation of the unigenes from P. viridis mantle transcriptome.

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Fig 8.

KOG annotation of the unigenes from P. viridis mantle transcriptome.

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Fig 9.

COG annotation of the unigenes from P. viridis mantle transcriptome.

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Table 1.

The candidate mantle transcripts involved in biomineralization from P. viridis mantle.

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Table 2.

The MS information of the four samples extracted from P. viridis shell.

M-AIS, the acid-insoluble sample from myostracum layer. M-AS, the acid-soluble sample from myostracum layer. N-AIS, the acid-insoluble sample from nacre layer. N-AS, the acid-soluble sample from nacre layer.

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Fig 10.

Functionally annotation of the myostracum SMPs identified from P. viridis shell.

A: COG annotation of the SMPs from myostracum layer; B: GO annotation of the SMPs from myostracum layer.

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Fig 11.

Functionally annotation of the nacre SMPs identified from P. viridis shell.

A: COG annotation of the SMPs from the nacrelayer; B: GO annotation of the SMPs from the nacre layer.

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Table 3.

The top 10 KEGG pathways of the identified proteins from the nacre and the myostracum layer of P. viridis shell.

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Table 4.

SMPs identified with more than two matched peptides from the P. viridis shell by LC-MS/MS.

The MS/MS spectra were used for searching against the Illumina-sequencing based P. viridis mantle transcriptome using Mascot software. N represents the nacre layer and M represents the myostracum layer.

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Table 5.

Comparison of SMPs with domain features in the shells of various Bivalves.

The “√” indicates identification of this protein in this species.

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