Fig 1.
S, susceptible; R, resistant; Non, non-infected.
Table 1.
List of target genes for qPCR validation and assay IDs according to the manufacturer.
Fig 2.
Least square means of fecal egg counts (FEC) and packed cell volume (PCV) in resistant (r) and susceptible (s) Creole kids infected with 10,000 H. contortus larvae (L3) and non-infected (n) animals.
(a) first infection, (b) second infection.
Table 2.
Correlation coefficients between parasitological and physiological variables at slaughter.
Table 3.
Number of genes differentially expressed for each comparison.
Fig 3.
Top 5 biological processes that changed among groups.
Infected versus non-infected (Inf. vs non-inf.), resistant versus susceptible (Res. vs sus.).
Fig 4.
Top 5 cellular components and molecular functions that changed among groups.
Infected versus non-infected (Inf. vs non-inf.), resistant versus susceptible (Res. vs sus.).
Table 4.
Top 5 significant canonical pathways identified by Ingenuity pathway analysis using DE genes.
Table 5.
Top 5 significant KEGG pathways identified by DAVID using DE genes.
Table 6.
Top 5 upstream regulators identified by Ingenuity pathway analysis using DE genes.
Fig 5.
Top 5 diseases and biological function identified by Ingenuity pathway analysis using DE genes.
Fig 6.
Genes controlling cell survival that were differently expressed in infected versus non-infected mucosal tissue.
Fig 7.
Genes controlling cell survival that were differently expressed in resistant versus susceptible mucosal tissue.
Table 7.
Top 5 networks for each comparison identified by Ingenuity pathway analysis using DE genes.
Fig 8.
Comparison of fold changes of deferentially expressed genes measured by RNA-Seq (black) and qPCR analyses (white) according to the groups (resistant vs. susceptible, R/S and infected vs. non-infected, I/NI) and the tissues (mucosa and lymph nodes).