Table 1.
Overview of the patients enrolled in the study.
The other category includes: unknown (10), urinary infection (1), meningitis (2), hepatitis (1), and fever (1). Information on gender was missing for three and on age for two children.
Fig 1.
(A) Microbial landscape found in serum samples in Ugandan children. Each column represents a febrile child. Results for GB virus C and torque teno virus, which are of uncertain clinical significance, are not included. (B) Microbial landscape found in nasopharyngeal (NP) swab samples in Ugandan children. Note that bacterial species were not considered in Fig 1B. Each column represents a febrile child, and the color bars represent the total reads per million (rpM) of a particular microbe present in the sample. Results for GB virus C and torque teno virus, which are of uncertain clinical significance, are not included.
Fig 2.
Characterization of the novel orthobunyavirus identified in a febrile child.
(A) Schematic representation of the large (L) or RNA dependent RNA polymerase, medium (M) or polyprotein of Gn, NSm and Gc proteins and small (S) segment encoding the nucleocapsid (N) protein of Nyangole virus and percentage identity with the most closely related virus. Phylogenetic tree of all complete orthobunyavirus genome sequences along with Nyangole virus are represented in (B) for the RNA dependent RNA polymerase and (C) for the glycoprotein.
Fig 3.
Phylogenetic tree of all complete HRV-C genomes from NCBI (with information on country of isolation) and HRV-C genomes assembled in this study.