Fig 1.
Household contacts with persistently negative latent Mycobacterial tuberculosis infection at 12 months (pLTBI-) despite exposure to adults with culture-confirmed pulmonary tuberculosis).
Consort diagram showing the number of household contacts with persistently negative latent Mycobacterial tuberculosis infection in 12 months (pLTBI-) despite exposure to adults with culture-confirmed pulmonary tuberculosis.
Fig 2.
Figa: Household contacts of adult culture confirmed pulmonary TB cases with latent TB infection, persistently negative latent TB infection, resisters and complete absence of infection by TST and QFT-GIT. Fig 2B: Box plot diagram showing tuberculin skin test (TST; X-axis) and QuantiFERON TB Gold Test-in-tube (QFT-GIT; Y-axis) values for household contacts with latent TB infection. Fig 2C: Box plot diagram showing tuberculin skin test (TST; X-axis) and QuantiFERON TB Gold Test-in-tube (QFT-GIT; Y-axis) values for household contacts with persistently negative latent TB infection. Fig 2D: Box plot diagram showing TST (X-axis) and QFT-GIT (Y-axis) values for resister household contacts. Red line in Fig 2B, Fig 2C and Fig 2D represents the QFT-GIT value of 0.35IU/ml.
Table 1.
Demographic and clinical characteristics and factors associated with persistently negative latent Mycobacteria tuberculosis infection among household contacts of culture-confirmed pulmonary TB in India.
Table 2.
Exposure characteristics[6] associated with persistently negative latent Mycobacterium tuberculosis infection among household contacts of culture-confirmed pulmonary TB cases in India.
Fig 3.
Clustering of household contacts with persistently negative latent Mycobacterial tuberculosis infection (pLTBI-) in 39 households stratified by high and low tuberculosis (TB) case exposure is the Fig 3 title.
Square represents pLTBI- household contacts with high exposure, referred to as resisters. Orange shaded squares represents household members who share the bed with culture-confirmed pulmonary TB case. Shaded circles represent the household contacts with positive LTBI and blue are smear positive TB cases.