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Fig 1.

Flowchart of patients enrolled in our study.

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Table 1.

The patient characteristics of the study population.

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Fig 2.

A 53-year-old male with chronic hepatitis B infection and pathologic fibrosis stage 3.

While the passive driver was on the right chest wall: (a) MR magnitude images provided anatomic information, (b) Wave images from the MRE acquisition at 60 Hz showing propagating shear waves, (c) Region-of-interest (white-dashed line) for liver stiffness measurement was drawn on an elastogram with confidence mapping. The liver stiffness was 3.17 kPa. While the passive driver was on the left chest wall: (d) MR magnitude images provided anatomic information, (e) Wave images from the MRE acquisition at 60 Hz showing propagating shear waves, (f) Region-of-interest (white-dashed line) for spleen stiffness measurement was drawn on an elastogram with confidence mapping. The spleen stiffness was 6.63 kPa.

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Table 2.

The liver stiffness and spleen stiffness values at each fibrosis stage.

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Table 2 Expand

Fig 3.

Scatterplot with jittered points illustrating the relationship between liver/spleen stiffness, splenic volume and fibrosis stage.

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Fig 3 Expand

Table 3.

Correlation coefficients between liver/spleen stiffness, splenic volume and fibrosis stage.

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Table 3 Expand

Fig 4.

Receiver operating characteristic (ROC) curve for predicting advanced liver fibrosis (F3-F4).

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Fig 4 Expand

Table 4.

The statistical results of spleen stiffness, spleen volume, liver stiffness and the combination of spleen stiffness and liver stiffness for predicting advanced liver fibrosis (F3-F4).

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Table 4 Expand