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Fig 1.

Study population.

WHO = World Health Organization; VSP = Vanderbilt Specialty Pharmacy; *One patient received both sildenafil and tadalafil during study period. We utilized pharmacy claims data for both medications and created a record for both sildenafil and tadalafil for this patient.

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Table 1.

Baseline demographics for study population.

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Table 1 Expand

Table 2.

Baseline demographics by proportion of days covered (PDC).

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Table 2 Expand

Fig 2.

Boxplot illustrating modified non-adherence by patients reporting an adverse event.

Patient data represented using jittered dots. Due to a high proportion of patients with 0% modified non-adherence (i.e., 100% raw PDC score), the 25th percentile and the median both overlap at 0%. The top of the box represents the 75th percentile of the data. The y-axis only extends up to 50% because the highest modified non-adherence value was 46%. Modified non-adherence was calculated as 100 –raw PDC value in percentage (%).

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Fig 2 Expand