Fig 1.
Minimal Inhibitory Concentration [MIC] and Minimal Biofilm Eradication Concentration [MBEC] of gentamicin towards planktonic [P] and biofilm-forming [B] cells of P.aeruginosa [P.a], S.aureus [S.a.], K.pneumoniae [K.p.].
Asterisks show statistical significance [K-W test, p<0.05] between results obtained for P vs. B of particular microbial species.
Fig 2.
P.aeruginosa biofilm formed on HA surface.
Upper part of picture–multilayer form of mature P.aeruginosa biofilm [Magn.2500x]; lower part of picture–P.aeruginosa biofilm-forming cells [Magn.20000x]. Zeiss Evo Ma SEM.
Fig 3.
Comparison of Minimal Biofilm Eradication Concentration [MBEC] of gentamicin against biofilm formed on hydroxyapatite [HA] or polystyrene [Poly] surfaces by P.aeruginosa [P.a], S.aureus [S.a.], K.pneumoniae [K.p.] in 24-well plates.
Fig 4.
Comparison of the number of S.aureus biofilm-forming cells after gentamicin sponge application [GS] to the number of biofilm-forming cells of untreated control samples [C].
8,24,48 –stand for the hours of incubation of the analyzed sample within the sponge. For the Reader’s convenience, a logarithmic scale was applied here. All the differences between the respective control and analyzed biofilm samples are statistically significant (M-W test, p<0.05).
Fig 5.
Comparison of the number of P.aeruginosa biofilm-forming cells after gentamicin sponge application [GS] to the number of biofilm-forming cells of untreated control samples [C].
8,24,48 –stand for the hours of incubation of the analyzed sample within the sponge. All the differences between the respective control and analyzed biofilm samples are statistically significant (M-W test, p<0.05).
Fig 6.
Comparison of the number of K.pneumoniae biofilm-forming cells after gentamicin sponge application [GS] to the number of biofilm-forming cells of untreated control samples [C].
8,24,48 –stand for the hours of incubation of the analyzed sample within the sponge. Statistically significant differences between the respective control and analyzed biofilm samples are marked with an asterisk (M-W test, p<0.05).