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Fig 1.

Examples of focal liver lesions.

From left to right livers with an adenoma, cyst, HCC, hemangioma, and a metastasis from colorectal carcinoma origin are shown. The top row shows the arterial phases of the DCE-MRI and the bottom row the T2-weighted images. A zoom-in of the lesions is inserted.

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Fig 1 Expand

Table 1.

Features derived from DCE-MR and T2-weighted images and risk factors.

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Table 1 Expand

Fig 2.

Time-to-peak feature maps of a liver with a hemangioma (left) and a HCC (right).

The lesions correspond with the lesions in Fig 1. The red contours show the lesion segmentations.

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Fig 2 Expand

Table 2.

Classification results for the four different feature sets (sensitivity/specificity), with 19 features selected.

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Table 2 Expand

Table 3.

Selected features with the highest ANOVA F-scores.

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Table 3 Expand

Table 4.

Confusion matrix of the five class problem, including the sensitivity, specificity and one-versus-other accuracy per lesion class.

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Table 4 Expand

Fig 3.

ROC curves of all lesion classes in a one-versus-other approach.

The rest class is calculated as the outcome probabilities of the other four lesions.

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Fig 3 Expand

Table 5.

Areas under the ROC curve (AUC) for each class including the optimal cut-off value and the corresponding true positive rate (TPR), false positive rate (FPR) and false negative rate (FNR).

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Table 5 Expand

Fig 4.

ROC curve of benign-versus-malignant classification problem.

The area under the ROC curve (AUC) is 0.94.

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Fig 4 Expand